Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KWV95239.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (298 aa)    
Predicted Functional Partners:
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
 
 
 0.934
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.869
KWV94390.1
S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
  
 
0.859
KWV94814.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.767
KWV95242.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.759
KWV94813.1
DNA ligase-associated DEXH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.714
KWV94319.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.677
KWV93965.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
    
 0.677
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
       0.673
KWV96108.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.653
Your Current Organism:
Erythrobacter sp. AP23
NCBI taxonomy Id: 499656
Other names: E. sp. AP23
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