Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
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[Homology]
Score
KWV95287.1Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)    
Predicted Functional Partners:
KWV95285.1
2-hydroxychromene-2-carboxylate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.854
KWV95286.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.854
KWV95284.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.773
KWV94374.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
KWV95288.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
KWV94449.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
KWV95555.1
Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.427
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.418
Your Current Organism:
Erythrobacter sp. AP23
NCBI taxonomy Id: 499656
Other names: E. sp. AP23
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