STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vps10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1489 aa)    
Predicted Functional Partners:
Pc13g07220
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.833
Pc18g01990
Pc18g01990 protein.
    
 0.787
Pc22g07900
Pc22g07900 protein.
    
 
 0.780
Pc12g08450
Proteasome subunit alpha type.
    
 
 0.761
Pc14g01230
Pc14g01230 protein.
    
 
 0.761
Pc20g11580
Proteasome subunit alpha type.
    
 
 0.761
Pc13g10100
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.759
Pc20g05630
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.728
Pc22g05200
Pc22g05200 protein.
    
 
 0.728
Pc13g01790
AP-1 complex subunit gamma.
     
 0.712
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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