STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SsbKEGG: shn:Shewana3_3590 2.1e-09 single-strand binding protein K00655. (133 aa)    
Predicted Functional Partners:
SsbA_2
KEGG: shn:Shewana3_3590 2.6e-12 single-strand binding protein K00655; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.917
SsbA_1
Single-strand binding family protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 
0.905
topB
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
 
 0.840
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.840
dnaB
KEGG: cac:CAC3715 2.9e-31 dnaC; replicative DNA helicase, DNAC K02314; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.831
EEA86015.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.757
EEA86017.1
Hypothetical protein; KEGG: cac:CAC0943 0.00063 his_2; phosphoribosyl-ATP pyrophosphohydrolase K01523; Psort location: Cytoplasmic, score: 8.87.
       0.746
EEA86018.1
Hypothetical protein; KEGG: pfa:PFL1370w 0.00035 NIMA-related protein kinase (Pfnek-1) K08286; Psort location: Cytoplasmic, score: 8.87.
       0.746
EEA86019.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.746
DnaE
KEGG: tte:TTE1818 0. dnaE; DNA polymerase III alpha subunit K02337; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.746
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
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