STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (361 aa)    
Predicted Functional Partners:
EEA85897.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
     
 0.626
EEA84092.1
Hypothetical protein; KEGG: ecn:Ecaj_0478 0.0063 NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 K00339; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.567
EEA85135.1
Hypothetical protein; KEGG: vfi:VFA0135 7.0e-08 DNA helicase II K01529; Psort location: Cytoplasmic, score: 8.87.
  
     0.515
EsiB
Tetratricopeptide repeat protein; KEGG: eci:UTI89_C1133 1.6e-23 hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.507
EEA85107.1
Hypothetical protein.
 
     0.501
YjcD_1
UvrD/REP helicase; KEGG: sth:STH2968 1.9e-57 putative ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 8.87.
  
     0.496
Smc_4
Hypothetical protein; KEGG: cal:orf19.2410 5.1e-08 IMH1; involved in vesicular transport K01553; Psort location: Cellwall, score: 9.17.
 
     0.490
EEA85542.1
Methyltransferase domain protein; KEGG: spo:SPBC16E9.05 5.5e-07 putative delta-sterol c-methyltransferase K00559; Psort location: Cytoplasmic, score: 8.87.
 
     0.480
UgtP_2
Monogalactosyldiacylglycerol synthase, C-terminal domain protein; KEGG: sab:SAB0883c 4.4e-35 UDP-glucose diacylglycerol glucosyltransferase.
 
   
 0.467
PilE
Prepilin-type cleavage/methylation N-terminal domain protein.
 
     0.461
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
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