STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KdpD_1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cac:CAC3678 3.0e-219 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; Psort location: CytoplasmicMembrane, score: 10.00. (918 aa)    
Predicted Functional Partners:
KdpE
Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.1e-43 kdpE; transcriptional regulatory protein KdpE K07667; Psort location: Cytoplasmic, score: 9.98.
 0.996
KdpB_2
KEGG: cpf:CPF_1211 7.7e-86 kdpB; K+-transporting ATPase, B subunit K01545; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.960
kdpC
K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.928
KdpD_2
Hypothetical protein; KEGG: cac:CAC3678 4.1e-28 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 
0.928
kdpA
K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.918
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.894
EEA84860.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 7.63.
       0.459
GraR
Response regulator receiver domain protein; KEGG: chu:CHU_3042 9.0e-28 two-component response regulator K02483; Psort location: Cytoplasmic, score: 9.98.
 
 0.451
BasR
Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.2e-27 phoB; positive response regulator for pho regulon K07657; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.425
CorA_2
CorA-like protein; KEGG: fnu:FN0522 9.5e-05 exonuclease SBCC K03546; Psort location: Cytoplasmic, score: 8.87.
 
     0.401
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
Server load: low (16%) [HD]