STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QueG_2KEGG: bfr:BF4553 0.00025 fumarate reductase iron-sulfur cluster protein subunit K00240; Psort location: Cytoplasmic, score: 8.87. (320 aa)    
Predicted Functional Partners:
Ogt
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
      0.904
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.827
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.666
TrmL
Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
  
  
 0.614
MazG
MazG family protein; KEGG: pha:PSHAa0740 5.9e-40 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; Psort location: Cytoplasmic, score: 8.87.
  
     0.544
rusA
KEGG: aae:aq_1953 2.8e-08 putative crossover junction endodeoxyribonuclease rus K01160; Psort location: Cytoplasmic, score: 8.87.
       0.543
EEA84568.1
EDD domain protein, DegV family; Psort location: Cytoplasmic, score: 8.87.
       0.515
TmpC
Basic membrane protein.
       0.493
MetH
KEGG: ctc:CTC01806 1.4e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.456
CggR
Putative sugar-binding domain protein; KEGG: cpr:CPR_1160 1.6e-21 citrate lyase regulator, putative K00863; Psort location: Cytoplasmic, score: 8.87.
  
     0.452
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
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