STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addAATP-dependent nuclease subunit A; ATP-dependent DNA helicase. (1256 aa)    
Predicted Functional Partners:
addB
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
 
 0.999
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.871
SbcC
RecF/RecN/SMC N-terminal domain protein; KEGG: ctc:CTC00579 2.2e-65 sbcC; exonuclease sbcC K03546; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.866
EEA84434.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
     
 0.775
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.764
EEA85984.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.724
YjcD_1
UvrD/REP helicase; KEGG: sth:STH2968 1.9e-57 putative ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 8.87.
  
  
0.720
EEA84432.1
Hypothetical protein; KEGG: fnu:FN0592 3.9e-07 pcrA; ATP-dependent DNA helicase pcrA K03657; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.673
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.618
TrmK
Hypothetical protein; KEGG: sth:STH507 0.0044 ribosomal protein L11 methyltransferase K02687; Psort location: Cytoplasmic, score: 8.87.
 
     0.610
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
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