STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purHKEGG: cpf:CPF_0677 1.5e-137 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602:K01492; Psort location: Cytoplasmic, score: 8.87. (511 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 0.999
purM
KEGG: mta:Moth_2046 5.6e-90 phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.997
purB
Adenylosuccinate lyase; KEGG: cpf:CPF_1922 2.7e-170 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.87.
  
 0.996
purD
KEGG: cpr:CPR_0676 3.1e-114 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
 
 
 0.996
EEA84132.1
Hypothetical protein; KEGG: cac:CAC1655 2.1e-92 purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.989
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.987
GuaB_2
Putative inosine-5'-monophosphate dehydrogenase; KEGG: lin:lin0179 7.6e-221 similar to inosine monophosphate dehydrogenase K00088; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.982
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.979
fhs
KEGG: nme:NMB1839 2.0e-213 formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.87.
  
 0.978
PurL
Putative phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 1.6e-188 purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.972
Your Current Organism:
Clostridium hiranonis
NCBI taxonomy Id: 500633
Other names: Clostridium hiranonis DSM 13275, Clostridium hiranonis str. DSM 13275, Clostridium hiranonis strain DSM 13275, [. hiranonis DSM 13275, [Clostridium] hiranonis DSM 13275
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