| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX69209.1 | deoB | MITSMUL_04280 | MITSMUL_04014 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.408 |
| EEX69209.1 | glyA-2 | MITSMUL_04280 | MITSMUL_05620 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.431 |
| EEX69209.1 | nifJ | MITSMUL_04280 | MITSMUL_03798 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Pyruvate synthase. | 0.510 |
| EEX69209.1 | rpiB | MITSMUL_04280 | MITSMUL_04225 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Ribose-5-phosphate isomerase B; Psort location: Cytoplasmic, score: 8.96. | 0.677 |
| EEX69209.1 | rpiB-2 | MITSMUL_04280 | MITSMUL_04472 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Ribose-5-phosphate isomerase B. | 0.677 |
| EEX69209.1 | upp | MITSMUL_04280 | MITSMUL_05619 | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.819 |
| deoB | EEX69209.1 | MITSMUL_04014 | MITSMUL_04280 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | 0.408 |
| deoB | prs | MITSMUL_04014 | MITSMUL_05189 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.876 |
| deoB | rpiB | MITSMUL_04014 | MITSMUL_04225 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose-5-phosphate isomerase B; Psort location: Cytoplasmic, score: 8.96. | 0.706 |
| deoB | rpiB-2 | MITSMUL_04014 | MITSMUL_04472 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose-5-phosphate isomerase B. | 0.634 |
| deoB | tkt | MITSMUL_04014 | MITSMUL_05055 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.852 |
| glyA-2 | EEX69209.1 | MITSMUL_05620 | MITSMUL_04280 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | 0.431 |
| glyA-2 | nifJ | MITSMUL_05620 | MITSMUL_03798 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyruvate synthase. | 0.667 |
| glyA-2 | rpiB-2 | MITSMUL_05620 | MITSMUL_04472 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose-5-phosphate isomerase B. | 0.707 |
| glyA-2 | tkt | MITSMUL_05620 | MITSMUL_05055 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.400 |
| glyA-2 | upp | MITSMUL_05620 | MITSMUL_05619 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.920 |
| nifJ | EEX69209.1 | MITSMUL_03798 | MITSMUL_04280 | Pyruvate synthase. | 5'-nucleotidase, C-terminal domain protein; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | 0.510 |
| nifJ | glyA-2 | MITSMUL_03798 | MITSMUL_05620 | Pyruvate synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.667 |
| nifJ | pfkB | MITSMUL_03798 | MITSMUL_04212 | Pyruvate synthase. | 1-phosphofructokinase; Psort location: Cytoplasmic, score: 9.26; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.483 |
| nifJ | prs | MITSMUL_03798 | MITSMUL_05189 | Pyruvate synthase. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.530 |
