Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
typAGTP-binding protein TypA; KEGG: eci:UTI89_C4460 2.8e-287 typA, bipA, yihK, yjhK; putative GTP-binding factor K06207; Psort location: Cytoplasmic, score: 9.97. (607 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.747
rpsI
Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
    0.564
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
  
  
 0.558
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
  
 0.552
tsf
Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.552
MalL
Alpha amylase, catalytic domain protein; KEGG: lmf:LMOf2365_0270 1.2e-137 malL-2; oligo-1,6-glucosidase K01182; Psort location: Cytoplasmic, score: 9.26.
      
 0.552
RseB
MucB/RseB family protein; Psort location: Periplasmic, score: 9.44.
      
 0.552
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.546
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
   
  
 0.542
EFB73400.1
KEGG: pen:PSEEN3732 1.1e-157 ABC transporter, ATP-binding protein.
 
     0.538
Your Current Organism:
Providencia rustigianii
NCBI taxonomy Id: 500637
Other names: P. rustigianii DSM 4541, Providencia rustigianii DSM 4541, Providencia rustigianii str. DSM 4541, Providencia rustigianii strain DSM 4541
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