STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YhcR5'-nucleotidase, C-terminal domain protein; KEGG: rpc:RPC_1152 6.6e-135 5'-nucleotidase-like K01081; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. (539 aa)    
Predicted Functional Partners:
cpdB
KEGG: plu:plu3927 8.4e-302 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family.
 
 
0.992
udk
Uridine kinase; KEGG: plu:plu1556 4.6e-95 udk; uridine kinase (uridine monophosphokinase) (pyrimidine ribonucleoside kinase) K00876; Psort location: Cytoplasmic, score: 8.96.
  
 
  0.931
UshA_1
5'-nucleotidase, C-terminal domain protein; KEGG: plu:plu3828 1.4e-253 ushA; protein UshA precursor [includes: UDP-sugar hydrolase (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT)] K01081:K08077; Psort location: Periplasmic, score: 10.00; Belongs to the 5'-nucleotidase family.
  
  
 
0.926
add
Adenosine deaminase; KEGG: aha:AHA_0273 5.3e-126 add-1; adenosine deaminase K01488; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
  
 0.921
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.921
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.915
tdk
Thymidine kinase; KEGG: plu:plu2497 5.2e-80 tdk; thymidine kinase K00857.
 
  
  0.914
surE
5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.910
NadR
Nicotinamide-nucleotide adenylyltransferase; KEGG: plu:plu0553 4.6e-191 nadR; transcriptional regulator NadR K00952:K06210:K06211.
     
 0.909
cpdA
Ser/Thr phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
   
 
 0.908
Your Current Organism:
Providencia rustigianii
NCBI taxonomy Id: 500637
Other names: P. rustigianii DSM 4541, Providencia rustigianii DSM 4541, Providencia rustigianii str. DSM 4541, Providencia rustigianii strain DSM 4541
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.