STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCIndole-3-glycerol phosphate synthase; KEGG: ent:Ent638_2206 2.6e-214 trpC, trpF; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; K01609 indole-3-glycerol phosphate synthase K01817; Belongs to the TrpC family. (452 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.999
trpE
KEGG: ent:Ent638_2204 6.7e-255 anthranilate synthase component I K01657; Psort location: Cytoplasmic, score: 8.96.
 
 0.998
pabA
KEGG: ent:Ent638_3787 1.3e-91 para-aminobenzoate synthase component II K01664; Psort location: Cytoplasmic, score: 8.96.
  
 0.996
pabB
KEGG: ent:Ent638_2381 1.3e-194 aminodeoxychorismate synthase, subunit I K01665.
 
 0.990
entC
KEGG: ent:Ent638_1125 1.4e-190 isochorismate synthase; K02361 isochorismate synthase.
 
 
 0.972
EFC55638.1
Glycosyl transferase family, helical bundle domain protein; KEGG: mms:mma_0486 2.5e-65 trpD2; hypothetical protein.
 
  
 0.898
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
   
 0.725
hisE
phosphoribosyl-ATP diphosphatase; KEGG: ent:Ent638_2638 2.0e-97 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein K11755; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.723
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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