STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvYHTH-type transcriptional activator IlvY; KEGG: shn:Shewana3_3435 2.5e-17 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family. (296 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.747
lysR
KEGG: shn:Shewana3_3435 9.0e-16 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.574
EFC54372.1
LysR substrate binding domain protein; KEGG: spe:Spro_1399 6.9e-63 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.541
EFC54156.1
LysR substrate binding domain protein; KEGG: mmw:Mmwyl1_3712 1.9e-12 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.
  
     0.462
EFC57859.1
LysR substrate binding domain protein; KEGG: bph:Bphy_3707 5.5e-70 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.415
EFC55991.1
LysR substrate binding domain protein; KEGG: swd:Swoo_1123 9.4e-43 LysR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.405
panZ
Hypothetical protein; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.
  
     0.401
EFC57339.1
LysR substrate binding domain protein; KEGG: cak:Caul_4844 2.8e-10 LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.400
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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