node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC55838.1 | cpxP | ENTCAN_07433 | ENTCAN_09594 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | 0.770 |
EFC55838.1 | wecD | ENTCAN_07433 | ENTCAN_09667 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.771 |
EFC55838.1 | wecF | ENTCAN_07433 | ENTCAN_09670 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.773 |
EFC55838.1 | wzxE | ENTCAN_07433 | ENTCAN_09669 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.750 |
EFC55838.1 | wzyE | ENTCAN_07433 | ENTCAN_09671 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.773 |
EFC55838.1 | wzzE | ENTCAN_07433 | ENTCAN_09664 | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.683 |
cpxP | EFC55838.1 | ENTCAN_09594 | ENTCAN_07433 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | Hypothetical protein; KEGG: hip:CGSHiEE_02470 7.7e-16 pflA; pyruvate formate lyase-activating enzyme 1 K07286. | 0.770 |
cpxP | wecD | ENTCAN_09594 | ENTCAN_09667 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.765 |
cpxP | wecF | ENTCAN_09594 | ENTCAN_09670 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.771 |
cpxP | wzxE | ENTCAN_09594 | ENTCAN_09669 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.730 |
cpxP | wzyE | ENTCAN_09594 | ENTCAN_09671 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.769 |
cpxP | wzzE | ENTCAN_09594 | ENTCAN_09664 | Periplasmic repressor CpxP; Psort location: Periplasmic, score: 9.44. | Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.770 |
wecB | wecC | ENTCAN_09665 | ENTCAN_09666 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Nucleotide sugar dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. | 0.999 |
wecB | wecD | ENTCAN_09665 | ENTCAN_09667 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.885 |
wecB | wecE | ENTCAN_09665 | ENTCAN_09668 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.934 |
wecB | wecF | ENTCAN_09665 | ENTCAN_09670 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.843 |
wecB | wecG | ENTCAN_09665 | ENTCAN_09672 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.946 |
wecB | wzxE | ENTCAN_09665 | ENTCAN_09669 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.934 |
wecB | wzyE | ENTCAN_09665 | ENTCAN_09671 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.829 |
wecB | wzzE | ENTCAN_09665 | ENTCAN_09664 | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.908 |