STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFC53594.1Alpha amylase, catalytic domain protein; KEGG: cbt:CLH_1549 4.2e-111 trehalose-6-phosphate hydrolase K01226; Psort location: Cytoplasmic, score: 9.26. (527 aa)    
Predicted Functional Partners:
treP
KEGG: ent:Ent638_0439 1.9e-241 trehalose(maltose)-specific PTS system components IIBC; K02818 PTS system, trehalose-specific IIB component K02819; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.979
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.960
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
 
 
 0.959
treC
Alpha,alpha-phosphotrehalase; KEGG: ent:Ent638_0438 8.6e-278 trehalose-6-phosphate hydrolase K01226; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.915
crr
KEGG: stt:t0424 3.1e-83 crr; glucose-specific PTS system component; K02777 PTS system, glucose-specific IIA component; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.909
treA
Alpha,alpha-trehalase; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.
   
 
 0.906
treF
Alpha,alpha-trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
   
 
 0.906
EFC56194.1
Family 4 glycosyl hydrolase; KEGG: eca:ECA3226 6.1e-213 6-phospho-alpha-glucosidase K01232.
     
 0.904
EFC53592.1
KEGG: scl:sce9265 3.5e-20 ABC transporter permease; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.839
EFC53593.1
ABC transporter, permease protein; KEGG: xfn:XfasM23_1548 1.9e-42 monosaccharide-transporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.823
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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