Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OOC52786.1Prolyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S33 family. (318 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.884
OOC56844.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.884
OOC52835.1
Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.809
OOC52837.1
Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.809
OOC56253.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.764
OOC52836.1
Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.672
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  0.498
OOC56688.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.488
OOC56148.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.433
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.421
Your Current Organism:
Nocardiopsis sinuspersici
NCBI taxonomy Id: 501010
Other names: CCUG 57624, DSM 45277, N. sinuspersici, Nocardiopsis sinuspersici Hamedi et al. 2010, Nocardiopsis sp. HM6, UTMC 00102, strain HM6
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