Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OOC53905.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (802 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.980
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
   
 
 0.763
OOC54737.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.663
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 
 0.616
OOC53903.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
OOC54714.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.528
OOC53902.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.517
OOC53904.1
Pyridoxamine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.517
OOC53906.1
Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.515
OOC55365.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.459
Your Current Organism:
Nocardiopsis sinuspersici
NCBI taxonomy Id: 501010
Other names: CCUG 57624, DSM 45277, N. sinuspersici, Nocardiopsis sinuspersici Hamedi et al. 2010, Nocardiopsis sp. HM6, UTMC 00102, strain HM6
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