STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hoch_0550PFAM: beta-lactamase domain protein; KEGG: scl:sce9034 hypothetical protein. (278 aa)    
Predicted Functional Partners:
Hoch_1844
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; KEGG: bba:Bd1116 adenylate cyclase.
 
     0.653
Hoch_2304
Metal dependent phosphohydrolase; PFAM: GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; KEGG: mxa:MXAN_6298 GAF domain-containing protein.
     0.625
Hoch_4571
Adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Forkhead-associated protein; GAF domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Forkhead-associated protein; GAF domain protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase.
 
     0.621
Hoch_3250
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.446
Hoch_0549
KEGG: afw:Anae109_2814 hypothetical protein.
       0.441
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
       0.431
Your Current Organism:
Haliangium ochraceum
NCBI taxonomy Id: 502025
Other names: H. ochraceum DSM 14365, Haliangium ochraceum DSM 14365, Haliangium ochraceum SMP-2, Haliangium ochraceum str. DSM 14365, Haliangium ochraceum strain DSM 14365, myxobacterium SMP-2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.