STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hoch_3452TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C- methyltransferase. (525 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
Hoch_3924
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pla:Plav_2897 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.989
Hoch_5119
PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: afw:Anae109_4432 ferredoxin--nitrite reductase.
 
  
 0.951
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.949
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.939
Hoch_6447
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
  
 0.911
Hoch_3361
PFAM: cytochrome c assembly protein; KEGG: scl:sce2850 heme exporter protein C.
  
    0.893
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde-2,1- aminomutase.
 
  
 0.850
Hoch_5277
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: csa:Csal_0467 cobalamin (vitamin B12) biosynthesis CbiX protein.
 
  
 0.799
Hoch_6015
PFAM: aminotransferase class-III; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde-2,1- aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.798
Your Current Organism:
Haliangium ochraceum
NCBI taxonomy Id: 502025
Other names: H. ochraceum DSM 14365, Haliangium ochraceum DSM 14365, Haliangium ochraceum SMP-2, Haliangium ochraceum str. DSM 14365, Haliangium ochraceum strain DSM 14365, myxobacterium SMP-2
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