STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hoch_4142Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (451 aa)    
Predicted Functional Partners:
gshB
KEGG: scl:sce7568 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family.
 
  
 0.933
Hoch_0148
PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: tgr:Tgr7_1858 leucyl aminopeptidase; Belongs to the peptidase M17 family.
  
  
  0.913
Hoch_5783
PFAM: glutamate--cysteine ligase GCS2; KEGG: eba:ebA6981 glutamate--cysteine ligase.
    
  0.902
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
Hoch_1085
PFAM: aminotransferase class IV; KEGG: bgl:bglu_2g05740 putative branched-chain amino acid aminotransferase.
     
  0.900
Hoch_1758
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: hypothetical protein; K00681 gamma- glutamyltranspeptidase.
     
  0.900
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Hoch_3367
Branched-chain-amino-acid transaminase; PFAM: aminotransferase class IV; KEGG: afw:Anae109_2639 aminotransferase class IV.
     
  0.900
Hoch_3500
PFAM: gamma-glutamyltranspeptidase; KEGG: ank:AnaeK_4067 gamma-glutamyltransferase.
     
  0.900
Hoch_4488
PFAM: gamma-glutamyltranspeptidase; KEGG: scl:sce8286 gamma-glutamyltransferase.
     
  0.900
Your Current Organism:
Haliangium ochraceum
NCBI taxonomy Id: 502025
Other names: H. ochraceum DSM 14365, Haliangium ochraceum DSM 14365, Haliangium ochraceum SMP-2, Haliangium ochraceum str. DSM 14365, Haliangium ochraceum strain DSM 14365, myxobacterium SMP-2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.