STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hoch_6524Coproporphyrinogen dehydrogenase; KEGG: gur:Gura_0208 putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB. (431 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.943
Hoch_2765
PFAM: coproporphyrinogen III oxidase; KEGG: pin:Ping_2246 coproporphyrinogen III oxidase.
    
 0.933
Hoch_0384
PFAM: conserved hypothetical protein; KEGG: lpn:lpg1536 transmembrane protein.
    
 0.914
Hoch_5410
KEGG: pfl:PFL_5612 hypothetical protein.
    
 0.914
Hoch_6526
PFAM: AMP-dependent synthetase and ligase; KEGG: reh:H16_A2807 acyl-CoA synthetase (AMP- forming)/AMP-acid ligase II.
 
     0.799
Hoch_6523
Hypothetical protein.
       0.773
Hoch_6525
KEGG: azo:azo3252 hypothetical protein.
       0.773
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
   
 0.741
Hoch_6520
PFAM: Polynucleotide adenylyltransferase region; KEGG: rpi:Rpic_2862 poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.683
Hoch_6521
KEGG: afr:AFE_1817 sulfotransferase domain protein.
  
    0.676
Your Current Organism:
Haliangium ochraceum
NCBI taxonomy Id: 502025
Other names: H. ochraceum DSM 14365, Haliangium ochraceum DSM 14365, Haliangium ochraceum SMP-2, Haliangium ochraceum str. DSM 14365, Haliangium ochraceum strain DSM 14365, myxobacterium SMP-2
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