node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hoch_1746 | Hoch_2953 | Hoch_1746 | Hoch_2953 | PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_4405 peptide synthetase. | PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. | 0.961 |
Hoch_1746 | Hoch_6894 | Hoch_1746 | Hoch_6894 | PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_4405 peptide synthetase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.886 |
Hoch_1746 | hliL | Hoch_1746 | Hoch_1178 | PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_4405 peptide synthetase. | PFAM: Acyl transferase; Beta-ketoacyl synthase; KEGG: mxa:MXAN_4402 non-ribosomal peptide synthetase. | 0.966 |
Hoch_2953 | Hoch_1746 | Hoch_2953 | Hoch_1746 | PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. | PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_4405 peptide synthetase. | 0.961 |
Hoch_2953 | Hoch_6894 | Hoch_2953 | Hoch_6894 | PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.754 |
Hoch_4556 | Hoch_6894 | Hoch_4556 | Hoch_6894 | PFAM: Aldehyde Dehydrogenase; aminotransferase class-III; KEGG: bba:Bd0131 succinylglutamic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.612 |
Hoch_4556 | bioB | Hoch_4556 | Hoch_0506 | PFAM: Aldehyde Dehydrogenase; aminotransferase class-III; KEGG: bba:Bd0131 succinylglutamic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.759 |
Hoch_4556 | bioD | Hoch_4556 | Hoch_6892 | PFAM: Aldehyde Dehydrogenase; aminotransferase class-III; KEGG: bba:Bd0131 succinylglutamic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.756 |
Hoch_6894 | Hoch_1746 | Hoch_6894 | Hoch_1746 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_4405 peptide synthetase. | 0.886 |
Hoch_6894 | Hoch_2953 | Hoch_6894 | Hoch_2953 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. | 0.754 |
Hoch_6894 | Hoch_4556 | Hoch_6894 | Hoch_4556 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: Aldehyde Dehydrogenase; aminotransferase class-III; KEGG: bba:Bd0131 succinylglutamic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.612 |
Hoch_6894 | Hoch_6896 | Hoch_6894 | Hoch_6896 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: scl:sce2518 RNA-binding protein. | 0.686 |
Hoch_6894 | bioA | Hoch_6894 | Hoch_6893 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.991 |
Hoch_6894 | bioB | Hoch_6894 | Hoch_0506 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.846 |
Hoch_6894 | bioD | Hoch_6894 | Hoch_6892 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.964 |
Hoch_6894 | hliL | Hoch_6894 | Hoch_1178 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: Acyl transferase; Beta-ketoacyl synthase; KEGG: mxa:MXAN_4402 non-ribosomal peptide synthetase. | 0.897 |
Hoch_6894 | mnmE | Hoch_6894 | Hoch_6895 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.773 |
Hoch_6894 | yidC | Hoch_6894 | Hoch_6897 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.617 |
Hoch_6896 | Hoch_6894 | Hoch_6896 | Hoch_6894 | PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: scl:sce2518 RNA-binding protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.686 |
Hoch_6896 | bioA | Hoch_6896 | Hoch_6893 | PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: scl:sce2518 RNA-binding protein. | Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.547 |