| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAK43765.1 | BAK45115.1 | EGYY_05520 | EGYY_20250 | Hypothetical protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein. | 0.918 |
| BAK43765.1 | guaA | EGYY_05520 | EGYY_24800 | Hypothetical protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.751 |
| BAK43765.1 | hisG | EGYY_05520 | EGYY_20090 | Hypothetical protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.547 |
| BAK43765.1 | prs | EGYY_05520 | EGYY_01940 | Hypothetical protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.921 |
| BAK45115.1 | BAK43765.1 | EGYY_20250 | EGYY_05520 | Hypothetical protein. | Hypothetical protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.918 |
| BAK45115.1 | guaA | EGYY_20250 | EGYY_24800 | Hypothetical protein. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.751 |
| BAK45115.1 | hisG | EGYY_20250 | EGYY_20090 | Hypothetical protein. | Hypothetical protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.547 |
| BAK45115.1 | prs | EGYY_20250 | EGYY_01940 | Hypothetical protein. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.921 |
| LysU | guaA | EGYY_07870 | EGYY_24800 | lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.966 |
| LysU | hisG | EGYY_07870 | EGYY_20090 | lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family. | Hypothetical protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.700 |
| LysU | prs | EGYY_07870 | EGYY_01940 | lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.864 |
| LysU | pyrE | EGYY_07870 | EGYY_24040 | lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family. | Hypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.551 |
| MutT-2 | prs | EGYY_23580 | EGYY_01940 | NTP pyrophosphohydrolase including oxidative damage repair enzyme. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.910 |
| RpiB | TktA | EGYY_21090 | EGYY_19750 | Ribose 5-phosphate isomerase RpiB. | Transketolase. | 0.914 |
| RpiB | TktA-2 | EGYY_21090 | EGYY_19760 | Ribose 5-phosphate isomerase RpiB. | Transketolase. | 0.911 |
| RpiB | guaA | EGYY_21090 | EGYY_24800 | Ribose 5-phosphate isomerase RpiB. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.494 |
| RpiB | prs | EGYY_21090 | EGYY_01940 | Ribose 5-phosphate isomerase RpiB. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.926 |
| TktA | RpiB | EGYY_19750 | EGYY_21090 | Transketolase. | Ribose 5-phosphate isomerase RpiB. | 0.914 |
| TktA | TktA-2 | EGYY_19750 | EGYY_19760 | Transketolase. | Transketolase. | 0.999 |
| TktA | prs | EGYY_19750 | EGYY_01940 | Transketolase. | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.905 |
