node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ada | Rpe | EGYY_17560 | EGYY_17550 | Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.669 |
Ada | nnrE | EGYY_17560 | EGYY_17570 | Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.718 |
Ada | tsaD | EGYY_17560 | EGYY_26550 | Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.497 |
BAK43614.1 | Rpe | EGYY_03910 | EGYY_17550 | Hypothetical protein. | Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.429 |
BAK43614.1 | nnrD | EGYY_03910 | EGYY_21780 | Hypothetical protein. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.497 |
BAK43614.1 | nnrE | EGYY_03910 | EGYY_17570 | Hypothetical protein. | Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.497 |
BAK43614.1 | tsaD | EGYY_03910 | EGYY_26550 | Hypothetical protein. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.786 |
BAK43901.1 | BAK44454.1 | EGYY_07040 | EGYY_12990 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Belongs to the DEAD box helicase family. | 0.903 |
BAK43901.1 | MutT-2 | EGYY_07040 | EGYY_23580 | Hypothetical protein; Belongs to the DEAD box helicase family. | NTP pyrophosphohydrolase including oxidative damage repair enzyme. | 0.770 |
BAK43901.1 | SrmB-2 | EGYY_07040 | EGYY_11780 | Hypothetical protein; Belongs to the DEAD box helicase family. | Superfamily II RNA helicase; Belongs to the DEAD box helicase family. | 0.905 |
BAK43901.1 | nnrD | EGYY_07040 | EGYY_21780 | Hypothetical protein; Belongs to the DEAD box helicase family. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.765 |
BAK43901.1 | nnrE | EGYY_07040 | EGYY_17570 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.770 |
BAK43901.1 | tsaD | EGYY_07040 | EGYY_26550 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.413 |
BAK44454.1 | BAK43901.1 | EGYY_12990 | EGYY_07040 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Belongs to the DEAD box helicase family. | 0.903 |
BAK44454.1 | MutT-2 | EGYY_12990 | EGYY_23580 | Hypothetical protein; Belongs to the DEAD box helicase family. | NTP pyrophosphohydrolase including oxidative damage repair enzyme. | 0.770 |
BAK44454.1 | SrmB-2 | EGYY_12990 | EGYY_11780 | Hypothetical protein; Belongs to the DEAD box helicase family. | Superfamily II RNA helicase; Belongs to the DEAD box helicase family. | 0.902 |
BAK44454.1 | nnrD | EGYY_12990 | EGYY_21780 | Hypothetical protein; Belongs to the DEAD box helicase family. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.765 |
BAK44454.1 | nnrE | EGYY_12990 | EGYY_17570 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.770 |
BAK44454.1 | tsaD | EGYY_12990 | EGYY_26550 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.413 |
MutT-2 | BAK43901.1 | EGYY_23580 | EGYY_07040 | NTP pyrophosphohydrolase including oxidative damage repair enzyme. | Hypothetical protein; Belongs to the DEAD box helicase family. | 0.770 |