STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_02866Uncharacterized protein. (826 aa)    
Predicted Functional Partners:
PAAG_02262
Pre-mRNA-splicing factor cef1.
   
   0.966
PAAG_06529
Uncharacterized protein.
   
 
 0.965
PAAG_08137
U1 snRNP splicing complex subunit (Luc7).
   
 
 0.931
PAAG_05711
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.929
PAAG_02577
RRM domain-containing protein.
    
 
 0.924
PAAG_02078
Branchpoint-bridging protein.
    
 
 0.914
PAAG_06974
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
    
 
 0.871
PAAG_03277
Pre-mRNA-processing factor 39.
    
 
 0.867
PAAG_02840
Pre-mRNA-processing ATP-dependent RNA helicase prp5.
   
 
 0.859
PAAG_02602
Uncharacterized protein.
   
   0.858
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.