STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_03970Replication factor-A protein. (333 aa)    
Predicted Functional Partners:
PAAG_00294
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.999
PAAG_07572
RAD52 DNA repair protein RADC.
    
 0.977
PAAG_01496
UVSB PI-3 kinase; Belongs to the PI3/PI4-kinase family.
   
 0.972
PAAG_04117
DNA polymerase eta.
   
 
 0.961
PAAG_05972
N-acetyltransferase ECO1.
   
 
 0.961
PAAG_05997
H15 domain-containing protein.
    
 0.949
PAAG_05588
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
 0.949
PAAG_03308
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.935
PAAG_03621
Replication factor C subunit 2.
   
 0.912
PAAG_01009
DNA repair protein RAD14.
    
 0.910
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.