STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_054812-isopropylmalate synthase. (647 aa)    
Predicted Functional Partners:
PAAG_03296
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.989
PAAG_00014
Dihydroxy-acid dehydratase.
  
 
 0.970
PAAG_04401
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.970
PAAG_05776
Dihydroxy-acid dehydratase.
  
 
 0.970
PAAG_06072
Branched-chain-amino-acid aminotransferase.
  
 0.953
PAAG_02653
Acetyl-coenzyme A synthetase.
  
 
 0.929
PAAG_03447
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.919
PAAG_07786
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.919
PAAG_04542
Malate synthase; Belongs to the malate synthase family.
   
 
 0.914
PAAG_07605
Acetolactate synthase small subunit.
  
 
 0.913
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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