STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_06965ISWI chromatin-remodeling complex ATPase ISW1. (1130 aa)    
Predicted Functional Partners:
PAAG_00126
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.982
PAAG_08552
Uncharacterized protein.
    
 0.957
PAAG_08875
Histone acetyltransferase type B subunit 2.
   
 0.957
PAAG_02892
CBFD_NFYB_HMF domain-containing protein.
    
 0.949
PAAG_03081
PHD-type domain-containing protein.
    
 0.945
PAAG_08918
Histone H2B; Belongs to the histone H2B family.
   
 0.940
PAAG_08917
Histone H2A; Belongs to the histone H2A family.
   
 0.910
PAAG_08471
Histone H2A; Belongs to the histone H2A family.
   
 0.889
PAAG_11682
Uncharacterized protein.
   
 0.837
PAAG_08543
Uncharacterized protein.
   
 
 0.792
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.