STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_08597Thymidylate synthase. (360 aa)    
Predicted Functional Partners:
PAAG_08913
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
  
 
 0.995
PAAG_00286
Deoxycytidylate deaminase.
  
 
 0.986
PAAG_04821
Methylenetetrahydrofolate dehydrogenase.
  
 
 0.977
PAAG_05611
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
  
 0.977
PAAG_04297
Thymidylate kinase.
  
 
 0.971
PAAG_07412
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.964
PAAG_08512
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.964
PAAG_05944
Dihydrofolate reductase.
  
 
 0.957
PAAG_08349
C-1-tetrahydrofolate synthase.
  
 
 0.953
PAAG_03045
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
    
 0.946
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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