STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PADG_03844SHNi-TPR domain-containing protein. (464 aa)    
Predicted Functional Partners:
PADG_07156
Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.
   
 
 0.986
PADG_00718
Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
   
 
 0.979
PADG_05709
Histone acetyltransferase type B subunit 2.
   
 
 0.937
PADG_07134
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.809
PADG_00872
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.804
PADG_00873
Histone H3.
   
 
 0.803
PADG_04791
Histone H3-like centromeric protein CSE4.
   
 
 0.803
PADG_05571
Uncharacterized protein.
    
 
 0.731
PADG_05907
Histone H2B; Belongs to the histone H2B family.
    
 
 0.710
PADG_05906
Histone H2A; Belongs to the histone H2A family.
    
 
 0.705
Your Current Organism:
Paracoccidioides brasiliensis
NCBI taxonomy Id: 502780
Other names: P. brasiliensis Pb18, Paracoccidioides brasiliensis Pb18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.