STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B2J93_7561Uncharacterized protein. (541 aa)    
Predicted Functional Partners:
B2J93_257
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.950
B2J93_2707
SAP domain-containing protein.
     
 0.792
B2J93_977
ERCC4 domain-containing protein.
   
 
 0.780
B2J93_1212
ATP-dependent DNA helicase II subunit.
    
 0.756
B2J93_847
POLXc domain-containing protein.
    
 
 0.745
B2J93_8727
DNA lyase.
   
 
 0.729
B2J93_1171
DNA ligase.
   
 
 0.701
B2J93_559
HIT domain-containing protein.
    
 
 0.696
B2J93_8577
Polynucleotide kinase 3 phosphatase.
    
 
 0.690
B2J93_5241
ERCC4 domain-containing protein.
   
 
 0.687
Your Current Organism:
Marssonina coronariae
NCBI taxonomy Id: 503106
Other names: M. coronariae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.