STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPA92304.1PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED'. (235 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.881
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
  
  
  0.877
KPA87354.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
 0.874
KPA91625.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.862
nudC
Zn-finger containing NTP pyrophosphohydrolase; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain; Belongs to the Nudix hydrolase family. NudC subfamily.
   
 
 0.854
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.778
KPA93231.1
PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.775
KPA88050.1
Putative Rossmann fold nucleotide-binding protein; PFAM: Domain of unknown function (DUF3412); Possible lysine decarboxylase; Domain of unknown function (DUF4478).
 
  
  0.759
KPA92305.1
ADP-ribose pyrophosphatase; PFAM: NUDIX domain.
 
 
  0.758
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
  0.756
Your Current Organism:
Pseudomonas fuscovaginae
NCBI taxonomy Id: 50340
Other names: CCUG 32780, CFBP 2065, CIP 106695, DSM 7231, ICMP 5940, LMG 2158, LMG:2158, NCPPB 3085, P. fuscovaginae, PDDCC 5940, PDDCC:5940, Pseudomonas fuscivaginae, strain 6801
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