| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KPA87835.1 | KPA88937.1 | PF66_05793 | PF66_04617 | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.431 |
| KPA87835.1 | KPA90431.1 | PF66_05793 | PF66_02491 | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | 0.787 |
| KPA87835.1 | KPA91559.1 | PF66_05793 | PF66_01841 | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.529 |
| KPA87835.1 | recA | PF66_05793 | PF66_00441 | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.915 |
| KPA88937.1 | KPA87835.1 | PF66_04617 | PF66_05793 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | 0.431 |
| KPA88937.1 | KPA90431.1 | PF66_04617 | PF66_02491 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | 0.586 |
| KPA88937.1 | KPA91130.1 | PF66_04617 | PF66_02011 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: impB/mucB/samB family. | 0.452 |
| KPA88937.1 | KPA91559.1 | PF66_04617 | PF66_01841 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.907 |
| KPA88937.1 | KPA91896.1 | PF66_04617 | PF66_01478 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA/RNA helicase, superfamily I; PFAM: UvrD-like helicase C-terminal domain; UvrD/REP helicase N-terminal domain. | 0.580 |
| KPA88937.1 | KPA93370.1 | PF66_04617 | PF66_00299 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | PFAM: YebG protein. | 0.899 |
| KPA88937.1 | dinB | PF66_04617 | PF66_00089 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.431 |
| KPA88937.1 | recA | PF66_04617 | PF66_00441 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.616 |
| KPA89746.1 | KPA90431.1 | PF66_03599 | PF66_02491 | PFAM: Bacterial protein of unknown function (DUF883). | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | 0.670 |
| KPA89746.1 | KPA91896.1 | PF66_03599 | PF66_01478 | PFAM: Bacterial protein of unknown function (DUF883). | DNA/RNA helicase, superfamily I; PFAM: UvrD-like helicase C-terminal domain; UvrD/REP helicase N-terminal domain. | 0.674 |
| KPA90431.1 | KPA87835.1 | PF66_02491 | PF66_05793 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: Domain of unknown function (DUF4113); impB/mucB/samB family C-terminal domain; impB/mucB/samB family. | 0.787 |
| KPA90431.1 | KPA88937.1 | PF66_02491 | PF66_04617 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.586 |
| KPA90431.1 | KPA89746.1 | PF66_02491 | PF66_03599 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | PFAM: Bacterial protein of unknown function (DUF883). | 0.670 |
| KPA90431.1 | KPA90432.1 | PF66_02491 | PF66_02492 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | Hypothetical protein. | 0.583 |
| KPA90431.1 | KPA91130.1 | PF66_02491 | PF66_02011 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: impB/mucB/samB family. | 0.787 |
| KPA90431.1 | KPA91559.1 | PF66_02491 | PF66_01841 | SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: Helix-turn-helix; Peptidase S24-like. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.597 |