node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPA89643.1 | KPA90574.1 | PF66_04093 | PF66_02635 | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E'. | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | 0.731 |
KPA89643.1 | amn | PF66_04093 | PF66_04300 | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E'. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.667 |
KPA89643.1 | surE | PF66_04093 | PF66_00536 | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E'. | Exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.670 |
KPA89643.1 | surE-2 | PF66_04093 | PF66_01343 | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E'. | Exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.670 |
KPA90574.1 | KPA89643.1 | PF66_02635 | PF66_04093 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E'. | 0.731 |
KPA90574.1 | KPA90998.1 | PF66_02635 | PF66_03076 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.687 |
KPA90574.1 | KPA91023.1 | PF66_02635 | PF66_03101 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.761 |
KPA90574.1 | KPA92304.1 | PF66_02635 | PF66_00980 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED'. | 0.731 |
KPA90574.1 | amn | PF66_02635 | PF66_04300 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.748 |
KPA90574.1 | ndk | PF66_02635 | PF66_00695 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.717 |
KPA90574.1 | ribB | PF66_02635 | PF66_01907 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.737 |
KPA90574.1 | ribB-2 | PF66_02635 | PF66_05572 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.737 |
KPA90574.1 | surE | PF66_02635 | PF66_00536 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | Exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.743 |
KPA90574.1 | surE-2 | PF66_02635 | PF66_01343 | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | Exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.680 |
KPA90998.1 | KPA90574.1 | PF66_03076 | PF66_02635 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | 0.687 |
KPA90998.1 | KPA91023.1 | PF66_03076 | PF66_03101 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.761 |
KPA90998.1 | ndk | PF66_03076 | PF66_00695 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.877 |
KPA90998.1 | ribB | PF66_03076 | PF66_01907 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.780 |
KPA90998.1 | ribB-2 | PF66_03076 | PF66_05572 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.780 |
KPA91023.1 | KPA90574.1 | PF66_03101 | PF66_02635 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. | 0.761 |