| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRZ20226.1 | coaD | KKKWG1_1047 | KKKWG1_0403 | Hydrolase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.617 |
| birA/coaX | coaBC | KKKWG1_0538 | KKKWG1_1790 | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.956 |
| birA/coaX | coaD | KKKWG1_0538 | KKKWG1_0403 | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.944 |
| birA/coaX | coaE | KKKWG1_0538 | KKKWG1_1906 | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.576 |
| birA/coaX | guaA | KKKWG1_0538 | KKKWG1_2135 | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.536 |
| coaBC | birA/coaX | KKKWG1_1790 | KKKWG1_0538 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.956 |
| coaBC | coaD | KKKWG1_1790 | KKKWG1_0403 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.946 |
| coaBC | coaE | KKKWG1_1790 | KKKWG1_1906 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.506 |
| coaBC | ribF | KKKWG1_1790 | KKKWG1_0516 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase; FMN adenylyltransferase]; Belongs to the ribF family. | 0.603 |
| coaBC | rsmJ | KKKWG1_1790 | KKKWG1_1793 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ribosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.454 |
| coaD | CRZ20226.1 | KKKWG1_0403 | KKKWG1_1047 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hydrolase. | 0.617 |
| coaD | birA/coaX | KKKWG1_0403 | KKKWG1_0538 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.944 |
| coaD | coaBC | KKKWG1_0403 | KKKWG1_1790 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.946 |
| coaD | coaE | KKKWG1_0403 | KKKWG1_1906 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.948 |
| coaD | guaA | KKKWG1_0403 | KKKWG1_2135 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.632 |
| coaD | kdpF | KKKWG1_0403 | KKKWG1_0860 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Homologs of previously reported genes of unknown function. | 0.584 |
| coaD | kdtA | KKKWG1_0403 | KKKWG1_0442 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.691 |
| coaD | ribF | KKKWG1_0403 | KKKWG1_0516 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase; FMN adenylyltransferase]; Belongs to the ribF family. | 0.633 |
| coaD | rsmD | KKKWG1_0403 | KKKWG1_0383 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Ribosomal RNA small subunit methyltransferase D. | 0.807 |
| coaD | rsmJ | KKKWG1_0403 | KKKWG1_1793 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Ribosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.669 |