STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.907
ans
Asparaginase.
     
 0.854
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.807
birA/coaX
Bifunctional enzyme BirA/CoaX [Includes: Biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
  
 0.805
argG
Argininosuccinate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
     
  0.800
aspC
Aspartate aminotransferase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.800
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.800
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
     
  0.800
CRZ20156.1
Major facilitator superfamily MFS_1 transporter.
  
  
 0.562
Your Current Organism:
Kingella kingae
NCBI taxonomy Id: 504
Other names: ATCC 23330, CCUG 352, CIP 80.16, DSM 7536, K. kingae, Kingella kingii, Moraxella kingae, Moraxella kingii, NCTC 10529
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