STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menA1,4-dihydroxy-2-naphthoateoctaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (297 aa)    
Predicted Functional Partners:
Slin_2909
PFAM: thioesterase superfamily protein; KEGG: ppd:Ppro_2603 hypothetical protein.
 
  
 0.950
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
    
 0.909
Slin_3006
Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
    
 0.841
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.834
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.823
Slin_1750
KEGG: lip:LI0806 O-succinylbenzoic acid--CoA ligase.
 
   
 0.801
Slin_0770
PFAM: Chorismate binding-like; KEGG: dps:DP0254 isochorismate synthase (MenF).
 
   
 0.796
Slin_2020
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: dps:DP0251 N-acylamino acid racemase (MenC).
 
   
 0.771
Slin_0040
Peroxiredoxin; PFAM: glutathione peroxidase; KEGG: hypothetical protein.
       0.603
argS
arginyl-tRNA synthetase; KEGG: bba:Bd2027 hypothetical protein; TIGRFAM: arginyl-tRNA synthetase.
       0.473
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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