STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_0059Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: dds:Ddes_0769 two component, sigma54 specific, transcriptional regulator, fis family. (446 aa)    
Predicted Functional Partners:
Slin_0631
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; KEGG: stt:t3237 RNA polymerase factor sigma-54.
 
  
 0.790
Slin_3102
Signal transduction histidine kinase with CheB and CheR activity; KEGG: eba:ebA2146 regulator protein; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; PAS fold-3 domain protein; CheB methylesterase; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; histidine kinase A domain protein; ATP- binding region ATPase domain protein; PAS domain containing protein.
  
 
 0.713
Slin_0754
KEGG: dol:Dole_0426 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; PAS fold- 4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
 
 
 0.563
Slin_0068
KEGG: mxa:MXAN_0168 sensory box histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.532
Slin_6561
KEGG: similar to sensory histidine protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; CHASE3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; ATP-binding region ATPase domain protein.
  
 
 0.488
Slin_0058
PFAM: Glycoside hydrolase 97; KEGG: sfr:Sfri_1777 alpha-glucosidase.
  
    0.480
Slin_2346
PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; KEGG: sdn:Sden_2846 ATP-binding region, ATPase-like protein.
 
 
 0.466
Slin_0621
KEGG: dar:Daro_4142 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver; PAS domain containing protein.
  
 
 0.458
Slin_3312
Multi-sensor hybrid histidine kinase; KEGG: aha:AHA_2188 PAS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.458
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
   
 0.431
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.