STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_1610Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: pca:Pcar_1952 negative regulator of ferric uptake; Belongs to the Fur family. (174 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.702
Slin_1184
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; KEGG: rpe:RPE_4614 hypothetical protein.
  
    0.689
Slin_1611
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.637
Slin_1987
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.632
Slin_0646
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mxa:MXAN_1564 alkyl hydroperoxide reductase C.
  
  
 0.627
Slin_0701
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; Redoxin domain protein; KEGG: rpi:Rpic_0704 peroxidase.
  
  
 0.627
Slin_3018
KEGG: dat:HRM2_45510 hypothetical protein.
  
    0.600
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.585
Slin_1609
KEGG: cak:Caul_3448 hypothetical protein.
       0.560
Slin_0245
TIGRFAM: signal peptidase I; PFAM: Peptidase S24, S26A and S26B, conserved region; KEGG: glo:Glov_1621 signal peptidase I; Belongs to the peptidase S26 family.
   
    0.558
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.