Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slin_1908PFAM: isochorismatase hydrolase; KEGG: scl:sce2665 isochorismatase. (205 aa)    
Predicted Functional Partners:
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.626
Slin_1907
PFAM: glycoside hydrolase clan GH-D; KEGG: melibiase, putative.
       0.618
Slin_1906
Hypothetical protein.
       0.560
Slin_0010
PFAM: isochorismatase hydrolase; KEGG: bid:Bind_1386 isochorismatase hydrolase.
  
     0.554
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: NAD+ dependent glycerol-3-phosphate dehydrogenase, putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.546
Slin_1909
Hypothetical protein.
       0.543
Slin_4346
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
 
 
 0.511
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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