STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_2052TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: apa:APP7_1934 uroporphyrin-III C- methyltransferase. (266 aa)    
Predicted Functional Partners:
Slin_0478
TIGRFAM: siroheme synthase; KEGG: par:Psyc_1065 uroporphyrinogen-III C- methyltransferase / precorrin-2 dehydrogenase.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.989
Slin_2051
Sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: afw:Anae109_4432 ferredoxin--nitrite reductase.
 
  
 0.984
Slin_3227
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: AGAP008064-PA; K01719 uroporphyrinogen-III synthase.
  
 
 0.924
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.917
Slin_5405
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA2989 uroporphyrin-III C- methyltransferase.
  
  
 
0.903
Slin_5386
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bba:Bd3444 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.856
Slin_1697
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.780
Slin_5941
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; KEGG: nha:Nham_0662 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.767
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.736
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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