STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_3000TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: acp:A2cp1_2449 phosphodiesterase, MJ0936 family. (163 aa)    
Predicted Functional Partners:
Slin_0458
PFAM: Ankyrin; SMART: Ankyrin; KEGG: pat:Patl_1108 ankyrin.
  
 
 
 0.904
Slin_6026
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.859
Slin_0367
PFAM: protein of unknown function DUF450; KEGG: cjd:JJD26997_0689 DNA methylase-type I restriction-modification system.
  
     0.644
Slin_2999
PFAM: AMP-dependent synthetase and ligase; KEGG: maq:Maqu_2863 acyl-CoA synthetase.
   
   0.640
Slin_1306
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.618
Slin_0665
TIGRFAM: metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: hypothetical protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
 
 0.445
Slin_4487
Thioredoxin-related protein-like protein; KEGG: dat:HRM2_42220 putative thioredoxin.
  
     0.417
Slin_4754
KEGG: hypothetical protein.
  
    0.407
Slin_6501
PFAM: surface antigen (D15); KEGG: psa:PST_1545 surface antigen family outer membrane protein.
  
     0.402
Slin_2998
PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: hap:HAPS_1220 transport system nucleoside permease.
     
 0.401
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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