STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_3003TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: pst:PSPTO_0610 biotin--protein ligase. (269 aa)    
Predicted Functional Partners:
Slin_5246
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 
 0.933
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.928
Slin_3536
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: atc:AGR_L_580GM propionyl-CoA carboxylase alpha chain.
 
  
 0.899
Slin_5245
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.891
Slin_2390
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: similar to propionyl-CoA carboxylase alpha subunit; K01965 propionyl-CoA carboxylase alpha chain.
 
  
 0.831
Slin_1632
PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit.
 
 
 0.809
Slin_4454
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.794
Slin_4524
Biotin carboxylase-like protein; KEGG: bph:Bphy_7724 putative biotin carboxylase.
  
 0.776
Slin_5012
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: pca:Pcar_1437 malonyl CoA-acyl carrier protein transacylase.
 
   
 0.745
Slin_4899
Methylcrotonoyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: cvi:CV_1764 propionyl-CoA carboxylase (beta subunit).
  
 
 0.728
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (34%) [HD]