STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slin_3207Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_5659 integral membrane sensor signal transduction histidine kinase. (347 aa)    
Predicted Functional Partners:
Slin_5021
PFAM: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mxa:MXAN_4049 serine/threonine protein kinase/response regulator/adenylate cyclase.
 
 
 0.844
Slin_4603
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mrd:Mrad2831_5657 adenylate/guanylate cyclase.
 
 
   0.800
Slin_5022
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: met:M446_2799 response regulator receiver protein.
 
 
 
 0.786
Slin_3206
KEGG: hypothetical protein.
       0.773
Slin_2507
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: sfr:Sfri_1020 two component, sigma54 specific, transcriptional regulator, fis family protein.
 
 
 0.721
Slin_1041
Multi-sensor signal transduction histidine kinase; KEGG: azo:azo2450 putative two-component system sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 
0.633
Slin_3671
PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: geo:Geob_0176 transcriptional regulator, NifA subfamily, Fis family.
 
 
 0.633
Slin_0621
KEGG: dar:Daro_4142 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver; PAS domain containing protein.
 
 
 0.615
Slin_3312
Multi-sensor hybrid histidine kinase; KEGG: aha:AHA_2188 PAS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.613
Slin_1039
KEGG: pla:Plav_0648 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
   
 
 0.586
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.