STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_3715Histidine kinase; PFAM: ATP-binding region ATPase domain protein; TPR repeat-containing protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; KEGG: scl:sce8887 protein kinase. (695 aa)    
Predicted Functional Partners:
Slin_5021
PFAM: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mxa:MXAN_4049 serine/threonine protein kinase/response regulator/adenylate cyclase.
 
 
 0.858
Slin_5022
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: met:M446_2799 response regulator receiver protein.
 
 
 
 0.802
Slin_4603
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mrd:Mrad2831_5657 adenylate/guanylate cyclase.
 
 
 
 0.795
Slin_1039
KEGG: pla:Plav_0648 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 
 0.632
Slin_1035
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; CHASE3 domain protein; GAF domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein; histidine kinase HAMP region domain protein; KEGG: pfl:PFL_3251 sensor histidine kinase/response regulator.
  
 
 0.624
Slin_6561
KEGG: similar to sensory histidine protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; CHASE3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; ATP-binding region ATPase domain protein.
 
 
0.614
Slin_3142
KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.596
Slin_4198
KEGG: pna:Pnap_2875 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.595
Slin_1041
Multi-sensor signal transduction histidine kinase; KEGG: azo:azo2450 putative two-component system sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 
0.580
Slin_1031
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein; KEGG: gme:Gmet_2642 GAF sensor hybrid histidine kinase.
  
 
0.576
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.