STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa)    
Predicted Functional Partners:
Slin_5036
Citrate synthase I; KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase.
  
 0.994
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.969
Slin_2911
Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: gsu:GSU1700 malic enzyme.
  
 0.963
Slin_4767
KEGG: bba:Bd3723 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.943
Slin_4454
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.935
Slin_4403
PFAM: aminotransferase class I and II; KEGG: mno:Mnod_1959 aminotransferase class I and II.
  
 0.923
mqo
KEGG: avn:Avin_04080 malate:quinone-oxidoreductase; TIGRFAM: malate/quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase; FAD dependent oxidoreductase.
    
 0.917
Slin_2319
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: vvu:VV1_0553 glutamate synthase, large subunit.
  
 
 0.895
Slin_5648
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ppd:Ppro_1713 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.860
Slin_6640
KEGG: dal:Dalk_0221 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein.
    
 0.859
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.