STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_5536PFAM: GCN5-related N-acetyltransferase; KEGG: aha:AHA_0772 acetyltransferase. (139 aa)    
Predicted Functional Partners:
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
    0.777
hisA
1-(5-phosphoribosyl)-5-((5-phosphoribosylamino) methylideneamino)imidazole-4-carboxamideisomerase; PFAM: histidine biosynthesis protein; KEGG: hypothetical protein; K01814 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
    0.759
Slin_5535
Hypothetical protein.
       0.737
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
    0.512
Slin_0407
PFAM: argininosuccinate synthase; Queuosine synthesis-like; KEGG: mxa:MXAN_5108 argininosuccinate synthase.
  
  
 0.461
Slin_0410
PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_04390 acetyltransferase.
 
    0.449
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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