STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_5955KEGG: purB; adenylosuccinate lyase; K01756 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (446 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 0.997
purC
PFAM: SAICAR synthetase; KEGG: mxa:MXAN_2080 phosphoribosylaminoimidazole- succinocarboxamide synthase.
 
 0.990
purH
KEGG: oca:OCAR_4337 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region.
 
 0.988
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.932
Slin_5971
Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; KEGG: aci:ACIAD1323 amidophosphoribosyltransferase.
 
 
 0.926
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.920
Slin_6005
Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; KEGG: predicted protein; K01933 phosphoribosylformylglycinamidine cyclo-ligase.
 
 
 0.918
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mxa:MXAN_5107 argininosuccinate lyase.
    
 0.917
Slin_0368
TIGRFAM: AMP nucleosidase; PFAM: purine or other phosphorylase family 1; KEGG: bba:Bd1233 AMP nucleosidase.
    
 0.913
Slin_4342
PFAM: metallophosphoesterase; KEGG: similar to 5-nucleotidase; Belongs to the 5'-nucleotidase family.
  
 
 0.911
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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