STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_6027PFAM: peptidylprolyl isomerase FKBP-type; KEGG: maq:Maqu_0470 peptidylprolyl isomerase, FKBP- type. (304 aa)    
Predicted Functional Partners:
Slin_5201
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.925
Slin_1459
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
   
 0.666
Slin_5709
KEGG: rsh:Rsph17029_3728 HSP90 family molecular chaperone-like protein.
   
 0.666
Slin_1395
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: cja:CJA_1627 FKBP-type peptidyl-prolyl cis- trans isomerase.
  
   
 0.661
Slin_6026
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
   0.639
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.629
Slin_6028
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: gbm:Gbem_1305 phosphoesterase RecJ domain protein.
       0.591
Slin_6029
Nucleoside-diphosphate kinase; KEGG: GK19226 gene product from transcript GK19226- RA; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; Belongs to the NDK family.
  
   0.459
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
    
  0.448
Slin_4285
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dps:DP1247 ABC transporter ATP-binding protein.
  
 
 0.432
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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